This usually happens if you use "Clear history when Firefox closes" to clear the browsing history.

In case you use "Clear history when Firefox closes" or otherwise clear history.

• do not clear the Browsing History

• Options/Preferences -> Privacy & Security
  Firefox will: "Use custom settings for history":
  [X] "Clear history when Firefox closes" -> Settings
• https://support.mozilla.org/en-US/kb/delete-browsing-search-download-history-firefox

• clearing "Site Preferences" clears exceptions for cookies, images, pop-up windows, and software installation and exception for password and other website specific data
• clearing "Cookies" will remove all selected cookies including cookies with an allow exception you may want to keep

Your System Details list shows that you have a user.js file in the profile folder to initialize prefs# each time Firefox starts. The user.js file will only be present if you or other software has created this file and normally won't be present.

You can check its content with a text editor (right-click: "Open with"; do not double-click). The user.js file is read each time Firefox is started and initializes preferences to the value specified in this file, so preferences set via user.js can only be changed temporarily for the current session.

You can delete the user.js file if you didn't create this file yourself.

You can use the button on the "Help -> Troubleshooting Information" (about:support) page to go to the current Firefox profile folder or use the about:profiles page.

• Help -> Troubleshooting Information -> Profile Folder/Directory:
  Windows: Open Folder; Linux: Open Directory; Mac: Show in Finder
• https://support.mozilla.org/en-US/kb/profiles-where-firefox-stores-user-data