One potential cause is add-ons, and another is malware.

A standard diagnostic for add-on issues is to try Firefox's Safe Mode.

First, I recommend backing up your Firefox settings in case something goes wrong. See Back up and restore information in Firefox profiles. (You can copy your entire Firefox profile folder somewhere outside of the Mozilla folder.)

Next, restart Firefox in Firefox's Diagnose Firefox issues using Troubleshoot Mode using

Help > Restart with Add-ons Disabled

In the Safe Mode dialog, do not check any boxes, just click "Continue in Safe Mode."

Any luck?

You may want to run some supplemental security scans. These two tools are highly regarded:

Malwarebytes Anti-malware : http://www.malwarebytes.org/products/malwarebytes_free

SUPERAntiSpyware : http://www.superantispyware.com/

Do a malware check with some malware scanning programs on the Windows computer.
You need to scan with all programs because each program detects different malware.
Make sure that you update each program to get the latest version of their databases before doing a scan.

• http://www.malwarebytes.org/mbam.php - Malwarebytes' Anti-Malware
• http://www.superantispyware.com/ - SuperAntispyware
• http://www.microsoft.com/security/scanner/en-us/default.aspx - Microsoft Safety Scanner
• http://www.microsoft.com/windows/products/winfamily/defender/default.mspx - Windows Defender: Home Page
• http://www.safer-networking.org/en/index.html - Spybot Search & Destroy

You can also do a check for a rootkit infection with TDSSKiller.

• http://support.kaspersky.com/viruses/solutions?qid=208280684

See also:

• "Spyware on Windows": http://kb.mozillazine.org/Popups_not_blocked