I would suggest only using one (one of the ones you have installed, Adblock Edge, is end of life so you should remove it anyway). Having multiple will slow down Firefox and cause issues with websites.

If you have adjusted your filters and still have pop-ups, I'd suggest scanning for malware. Troubleshoot Firefox issues caused by malware

Also, you might check the reviews on some of these:

Some users accuse this one of actually adding ads: https://addons.mozilla.org/firefox/addon/ad-killer/reviews/

This one is not very well received, either: https://addons.mozilla.org/firefox/addon/ads-no-more/reviews/

I suspect that any content-modifying extension that hasn't been updated in the past 6 months is not going to be very effective since sites are watching for that now.