Note: Here are some forums that detail the same issue - none of the work-arounds provided here worked for me though.

http://forums.adobe.com/thread/737148

http://www.google.com/support/forum/p/Chrome/thread?tid=1ad7ca6c74d6b561&hl=en

This has been an issue since Firefox 4. wmode while also an issue is not what this is talking about. wmode="transparent" and possibly wmode="opaque" caused hand cursor issues in Firefox versions <3. Firefox 4 & 5 are simply missing hand cursor support entirely even when wmode="window".

C'mon Mozilla!! Be a pal and fix this bug.

https://support.mozilla.com/en-US/questions/797286

UPDATE:

I've sent the following email to: webmaster@mozilla.com

The flash player plugin for firefox on Mac has always worked properly until Firefox version 4 and 5. From within these versions, handcursors are not displayed when rolling over buttons .

The problem is in Firefox 4 and 5 on Mac - no hand cursors are showing up when viewing flash content.

Basically anything flash tries to do with the cursor fails - however, no other flash functionality fails (such as scripted or other animations that fire on roll over)

I understand that this has been reported as a known issue in your bug tracking - but currently isn't assigned to anyone. Does Mozilla intend to do anything about this?'

I'll post any response they give.

UPDATE: The webmaster address provides an auto-response full of apologies for not being able to answer questions.

I updated today to 5.1 and they still have not repaired this issue. I have updated twice now since this problem and I really wish they would pay attention to this because I use FF as a web development tool in my business.

Tested with FF6 beta. MouseCursors do show again