StopZilla is fine for Internet Explorer, but it doesn't do a very good job with other browsers.

You'd be much better off with Malwarebytes free edition from http://www.malwarebytes.org/

Also, many of your plugins are out of date which potentially exposes your system to attack. I'd recommend you update the following a.s.a.p.

Flash Player: http://get.adobe.com/flashplayer/

For more info, see Adobe releases security update for Flash Player

Shockwave For Director: http://get.adobe.com/shockwave/

Adobe Reader: http://get.adobe.com/reader/?promoid=BUIGO

See also Updates for Adobe Reader and Acrobat X brought forward

Java via Windows Control Panel | Java | Update

Thanks but does not solve the problem, same issue it ends up in the downloads box,click on it. Error Message - Application Not Found

Can you do this please.

In the location bar, type: about:config and hit Enter.

In the filter at the top, copy/paste the following setting: browser.download.manager.scanWhenDone which will bring it to the top.

Double click it to change it from True to False.

Close Firefox via File | Exit and then restart it again. Then go somewhere and download a file. When it finishes downloading, click the Downloads button and then right click the file and choose "Open Containing Folder" which should open the folder the file was downloaded to.