Can not scroll down list of messages quickly. When clicking on a message to open it, I get message "Not responding" then it opens after some delay
This has just occurred in the last two weeks. After clicking on a message to open it, nothing happens, and then I get the message "Thunderbird not responding" for a short while then the message opens. This can happen each time I open another message after it appears in the inbox.
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It is possible that when you select the email, it is being scanned by your anti-virus software and so stops further action - not responding - until the scan is complete.
First thing I would try is to disable your anti-virus scanning of emails. It will still scan any attachments you open.
If you are using an IMAP mail account, when you view subscribed folders only the header is downloaded. When you select an email then a copy of the folder is downloaded to a temporary folder to faciliate quicker access. Sunscribed Folders that have been synchronised to download a copy to the Thunderbird profile can also impact on performace. So you may experience some delay on occasions.
Another reason for slow reponses are folders that are large. You may not have many emails because you deleted some, but did you compact the folder to remove all traces of 'marked as deleted' emails?
To reduce the size of folders consider Archiving old emails including the Sent folder. Info on Archiving options:
Info on compacting - what it does and why it is important:
Good helpful info on maintaining a healthy Thunderbird: