Hello. I hope you can help me. We are using two Thunderbird profiles: "Sales" and "Purchases". We have thunderbird links for both of them on the desktop: This is how we call start the firefox profiles: Purchases: "C:\Program Files (x86)\Mozilla Thunderbird\thunderbird.exe" -no-remote -p Purchases Sales: "C:\Program Files (x86)\Mozilla Thunderbird\thunderbird.exe" -no-remote -p Sales (-no-remote is needed to start Thunderbird with two instances at once, -p <Profile> is to choose the profile) Everything works so far. Now we have an application which calls the "write"-dialog of thunderbird. (the dialog where you can send eMails) When calling the "write"-dialog, the fields of this dialog (from, to, subject, and the text body) should be filled by parameters. The application uses following call: thunderbird.exe -compose to=example@test.com,subject="example subject line",body="this is the example body" -no-remote -p Sales That means that the send dialog of the Sales-Profile-Thunderbird should be opened with the "sales" profile. (email receiver is filled with "example@text.com", subject is "example subject line", and the text is "this is the example body") The Problem: This works only if thunderbird with the "Sales" profile is not already running. If Thunderbird with the "Sales" profile is already running, Thunderbird is telling that the process is already running and should be closed first. Before adding the second profile "Purchases", we only used "Sales" profile, and we started thunderbird without "-no-remote -p Sales". With only one profile and without "-no-remote -p Sales", every worked well. But with 2 profiles, the user always have to close thunderbird first before calling the "write"-dialog from our application. Is there something I can do? Maybe changing the call used by our application to show the write-dialog? If you need more information, or something is not clear enough, let me know. Best regards M. Jaeger